Clinical Case Discussion - CA Larynx (Glottic CA) notes

My notes are helpful for anyone studying this subject, whether in the US, Australia, Europe, India, or anywhere else.

This note covers the following topics on Clinical Case Presentation of CA Larynx (Glottic CA) :

- How each point of history and clinical examination is important in reaching your provisional diagnosis.

- What is the importance of Past history, Family history, Personal history and Negative History?

- Questions asked in viva voce during examination.

- Causes of Change in voice

- Types of Change in voice

- What is Puberphonia, Rhinolalia Clausa, Rhinolalia Aperta?

- Define Hoarseness. What are the Danger signs of Hoarseness?

- Diurnal Variation in voice

- Causes of Pain during Speech

- What is a pack year?

- Carcinogens in Tobacco and Alcohol

- Mechanism of Carcinogenesis of Tobacco and Alcohol 

- Presentation of Supraglottic, Glottic & Subglottic Growth

- Hidden areas in Indirect Laryngoscopy

- What is Fixed vocal cord & Fixed hemilarynx?

- Causes of Fixed Vocal Cord

- Vocal Cord Paralysis VS Vocal Cord Fixity

- What is Transglottic Tumor?

- What is Laryngeal Crepitus & Bocca’s sign?

- Differential Diagnosis of CA Glottis

- Features of TB Laryngitis

- Most common site of CA Larynx

- Subsites of larynx

- Spread in Supraglottic, Glottic, Subglottic CA

- Natural Barriers for Spread of CA Larynx

- Neck Nodes in CA Larynx

- What is Broyle’s ligament?

- Spaces in Larynx -  Pre epiglottic Space of Boyer, Paraglottic Space, Reinke’s Space

- TNM Staging of Glottic CA

- Investigations in Glottic CA

- Radiological Features of Malignant Lymph Node

- Treatment plan in Glottic CA in T1, T2, T3, T4 stages

- Factors deciding treatment choice

- Radiotherapy Dose

- Contraindications, Advantages, Disadvantages, Complications of Radiotherapy

- What are Radiosensitizers?

- IMRT, IGRT

- ELS Classification of Cordectomy for Glottic CA

- Prognostic Factors of Glottic CA

- Survival Rates of CA Larynx

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